Brochure

skinbetter science brochure - SB6057

The Fastest-Growing Professional Skincare Brand in the United States.

2023 Kline Professional Skin Care: United States Market Analysis and Opportunities Report.

Don’t Just Take Our Word For It

AlphaRet Overnight Cream

16X AWARD WINNER

" Hands down this product is absolutely amazing ! "

+ Paige R. (actual customer)

Trio Rebalancing Moisture Treatment 4X AWARD WINNER " I'm blown away by this moisturizer! Quickly became a fav! "

+ Melissa (actual customer)

Techno Neck Perfecting Cream

4X AWARD WINNER " I have only been using this a few weeks and I can already see and feel the difference . I'll be 60 in two months. "

+ Jane (actual customer)

AlphaRet Exfoliating Peel Pads 4X AWARD WINNER

" These are on my list of skincare to never run out of ! Cannot believe what they do for my skin. " + Kate (actual customer)

Due to variability in photography lighting and printing, the actual color of the product may differ from that featured.

Listen to Real Life Users

InterFuse Treatment Cream EYE

2X AWARD WINNER

" After trying many eye creams, this is the only one that actually reduces [ the appearance of ] puffiness ! "

+ Honey (actual customer)

AlphaRet Clearing Serum 3X AWARD WINNER " I didn't think it was possible for my skin to look this good. "

+ Jim (actual customer)

Alto Advanced Defense and Repair Serum AWARD WINNER " What's not to love? Improves [the appearance of] skin texture, red tones and helps fight aging ! Truly the best! " + Logan (actual customer)

sun better TONE SMART SPF 68 Compact 5X AWARD WINNER " This is one of my holy grail products. " + Paige (actual customer)

Build a skin better Regimen

The “Where to Start” Regimen is our foundation to a pro- fessional skincare regimen. Next, add a moisturizer based on skin type. Then, select appropriate targeted treatments based on your skin concerns. And finally, finish with Cleanse and Prep.

WHERE TO START ANTIOXIDANTS

Alto Advanced Defense and Repair Serum ............................. 8 Alto Defense Serum ..................................................................... 9 Solo Hydrating Defense MEN ................................................... 10 SUNSCREENS sun better Advanced Mineral Protection Sunscreens ..................................................................................................... 11-13 RETINOIDS AlphaRet Overnight Cream ...................................................... 14 Intensive AlphaRet Overnight Cream ..................................... 14 AlphaRet Clearing Serum ......................................................... 15

ADAPT + BALANCE Mystro Active Balance Serum ............................................ 16-17

SKIN HEALTH DIETARY SUPPLEMENT BioRewind Skin Health Dietary Supplement .............................. 18 MOISTURIZE Trio Rebalancing Moisture Treatment .................................... 19 Trio Luxe Moisture Treatment ................................................ 20 Hydration Boosting Cream ....................................................... 21

TARGETED TREATMENTS FACE

InterFuse Treatment Cream FACE & NECK . ....................... 22 InterFuse Intensive Treatment LINES . .................................. 23 Even Tone Correcting Serum . ................................................ 24 AlphaRet Exfoliating Peel Pads .............................................. 25 EYE EyeMax AlphaRet Overnight Cream ..................................... 26 InterFuse Treatment Cream EYE ............................................. 27 Instant Effect Gel EYE .............................................................. 28 NECK Techno Neck Perfecting Cream ............................................. 29 BODY AlphaRet Body Overnight Cream ........................................... 30

CLEANSE + PREP

CLEANSER Refining Foam Cleanser ............................................................ 31 Cleansing Gel .............................................................................. 31 EXFOLIATING MASK Detoxifying Scrub Mask ........................................................... 31 REGIMENS Where to Start ........................................................................... 32 Clarity ........................................................................................... 33 Even Glow ................................................................................... 34

Where do I Start?

AM: Defend and Protect.

SELECT AN ANTIOXIDANT

Choose one of our antioxidant formulations that deploys a combination of Vitamins C and E, plus 17 other powerful antioxidants designed to synergistically provide a new level of comprehensive and dynamic defense against free radicals.

SELECT A SUNSCREEN

No matter your skin type or preference (oily or dry, light or dark complexion, tinted or sheer), if you are serious about the health of your skin, we have you covered.

The Skin Cancer Foundation recommends these products as effective broad-spectrum sunscreens.

The following pages provide information about skin better products. We always recommend that you work with your skincare provider to determine the right combination of products for your skin type and concerns.

Rejuvenate with a retinoid. Talk to your skincare provider to find the best one for your skin.

PM:

SELECT A RETINOID

AlphaRet is an exclusive technology that successfully combines a retinoid and an alpha hydroxy acid (AHA) for effective and tolerable skin rejuvenation. Address skin-aging concerns and explore our multiple award-winning retinoid collection.

Sunburn Alert: AlphaRet products contain an alpha hydroxy acid (AHA) that may increase your skin’s sensitivity to the sun and particularly the possibility of sunburn. Use a sunscreen, wear protective clothing and limit sun exposure while using this product and for a week afterwards. Caution: AlphaRet products contain retinoid in a topical form. If you are pregnant, lactating or planning to become pregnant, consult a physician before use. If using more than one exfoliating product, irritation may occur. For complete Usage Instructions, Sunburn Alert and Caution Statements, see product packaging.

Alto Advanced Defense and Repair Serum

AWARD WINNER

ANTIOXIDANT

Super-potent antioxidant serum that helps shield the skin against the effects of internal and external free radicals. Vitamins C and E, plus 17 additional free-radical fighters combined with a new antioxidant bring a new level of comprehensive defense.

IMPROVEMENT in the appearance of Skin Dullness * after 12 weeks

42%

After 12 weeks of twice-daily use, > 90% of patients reported: + An overall improvement in the appearance of their skin + That their skin was brighter looking and more radiant + That their skin was softer, smoother and more hydrated

BASELINE

AFTER 4 WEEKS, TWICE-DAILY USE**

*Average improvement evaluated in a clinical trial led by board-certified physician in 39 patients with twice-daily use over 12 weeks from baseline. **Unretouched clinical photography on clean, product-free skin. BASELINE AFTER 12 WEEKS, TWICE-DAILY USE**

Alto Defense Serum

3X AWARD WINNER

ANTIOXIDANT

An award-winning antioxidant complex designed to achieve a broad range of antioxidant protection from environmental oxidative stress.

IMPROVEMENT in the appearance of Redness * after 4 weeks IMPROVEMENT in the appearance of Fine Lines & Wrinkles * after 12 weeks

18%

37%

BASELINE

AFTER 4 WEEKS, TWICE-DAILY USE**

*Average improvement evaluated in a board-certified dermatologist-led clinical trial in 22 patients following twice-daily use over 12 weeks from baseline. **Unretouched clinical photography on clean, product-free skin. BASELINE AFTER 4 WEEKS, TWICE-DAILY USE**

Solo Hydrating Defense MEN

2X AWARD WINNER

ANTIOXIDANT

Clinically tested, once-daily skincare, engineered for men. Uniquely designed to provide male skin with an enhanced level of antioxidant defense against the environmental stressors of modern life. Supports healthier-looking skin.

IMPROVEMENT in the appearance of Pores * after 4 weeks IMPROVEMENT in the appearance of Skin Tone * after 4 weeks

28%

29%

After 12 weeks of once-daily use, 96% of patients reported: + Skin tone was more even-looking and felt smoother + The appearance of redness was reduced and it calmed and soothed skin after shaving

BASELINE

AFTER 4 WEEKS, ONCE-DAILY USE**

*Average improvement evaluated in a board-certified dermatologist-led clinical trial in 25 patients with once-daily use over 12 weeks from baseline. **Unretouched clinical photography on clean, product-free skin. BASELINE AFTER 8 WEEKS, ONCE-DAILY USE**

sun better Advanced Mineral Protection

SUNSCREEN

Serious protection against premature skin aging.

A.M.P. ( Advanced Mineral Protection ) : Achieving a Serious Level of Sun Protection + High-Performance Protection : 100% Mineral Actives, Up to SPF 75 + Choice : 5 formats and finishes for a serious and discerning skincare consumer + Beyond UV Benefits : IRA, HEVL/Blue Light, Pollution, Cosmetic Benefits

Scan here to learn expert application tips for our unique sunscreens and more!

The Skin Cancer Foundation recommends these products as an effective aid in the prevention of sun-induced damage to the skin, including sunburn and possibly premature aging. When used regularly in the prescribed manner, these products may also help reduce the potential risk of skin cancer due to overexposure to sunlight.

sun better Advanced Mineral Protection

SUNSCREEN

100 % Mineral Actives + High Sun Protection + UVA / UVB Broad Spectrum Protection

HEVL

IRA

HEVL / Blue Light

UVA/UVB

sun better TONE SMART BROAD SPECTRUM SPF 75 SUNSCREEN LOTION

4X AWARD WINNER

• Our highest level of sun protection in a tone-adapting, creamy lotion that provides a hint of color. • Acts as a primer under makeup or in place of a light coverage foundation. • Oil Free.

sun better SHEER BROAD SPECTRUM SPF 70 SUNSCREEN LOTION

• Our highest level of sheer sun protection in a resilient, creamy lotion. • Provides priming benefits alone or under makeup. • Oil Free.

Apply liberally and evenly 15 minutes before sun exposure. Reapply after 80 minutes of swimming or sweating, immediately after towel drying and at least every 2 hours. Children under 6 months: ask a doctor.

sun better When You're Serious About Your Skin

SUNSCREEN

80-Minute Water Resistance + Smoothing, Priming + Perfecting, Blurring, Mattifying

Pollution

Chemical-Free Actives

Reef Safe

sun better TONE SMART BROAD SPECTRUM SPF 68 SUNSCREEN COMPACT

5X AWARD WINNER

• High sun protection in a tone-adapting, silky smooth compact that provides a hint of blendable color. • Acts as a primer and can be layered for additional coverage.

sun better SHEER BROAD SPECTRUM SPF 56 SUNSCREEN COMPACT

AWARD WINNER

• High sun protection in a weightless, transparent, silky smooth compact. • Provides priming benefits with no tint.

sun better SHEER BROAD SPECTRUM SPF 56 SUNSCREEN STICK

5X AWARD WINNER

• High sun protection in a weightless, transparent, easy-to-apply stick. • Excellent for on-the-go use.

AlphaRet Overnight Cream Intensive AlphaRet Overnight Cream

17X AWARD WINNER

RETINOID

AlphaRet Technology is a unique molecule made up of retinoid and an AHA for effective and tolerable skin rejuvenation. AlphaRet Overnight Cream combines AlphaRet Technology with glycolic acid and other skin-hydrating and supporting ingredients to deliver retinoid renewing benefits with little-to-no irritation, for aging skin. †

IMPROVEMENT in the appearance of Fine Lines & Wrinkles * after 12 weeks IMPROVEMENT in the appearance of Skin Tone * after 12 weeks

33%

BASELINE

AFTER 8 WEEKS, NIGHTLY USE**

*Average improvement evaluated in a board-certified dermatologist-led clinical trial in 48 subjects with nightly use over 12 weeks from baseline. **Unretouched clinical photography on clean, product-free skin. † See sunburn alert and caution statements. BASELINE AFTER 8 WEEKS, NIGHTLY USE**

AlphaRet Clearing Serum

3X AWARD WINNER

RETINOID

AlphaRet Technology combined with salicylic acid, lactic acid and additional pore-clearing, hydrating and soothing ingredients, to rejuvenate and clarify the appearance of oilier, blemish-prone skin. †

IMPROVEMENT in the appearance of

50%

Skin Clarity * after 12 weeks

IMPROVEMENT in the appearance of Pores * after 12 weeks

25%

After 8 weeks of nightly use, 100% of patients agreed: + The overall appearance of their skin improved + Skin felt smoother + The overall appearance of their skin texture improved

BASELINE

AFTER 8 WEEKS, NIGHTLY USE**

BASELINE

AFTER 12 WEEKS, NIGHTLY USE**

*Average improvement evaluated in a board-certified dermatologist-led clinical trial in 20 subjects with nightly use over 12 weeks from baseline. **Unretouched clinical photography on clean, product-free skin. † See sunburn alert and caution statements.

Mystro Active Balance Serum

5X AWARD WINNER

ADAPT + BALANCE

A new way to achieve visible improvement in skin quality and glowing skin by uniquely supporting skin’s natural ability to adapt to stress and maintain balance.

After 12 weeks of twice-daily use, patients showed:

MEAN IMPROVEMENT in the appearance of Global Skin Quality

39%

Global Skin Quality was measured using combined visible attributes of redness, texture, dullness, pore size and uneven pigmentation.

BEFORE

AFTER 12 WEEKS, TWICE-DAILY USE* Above Average Result**

BEFORE

AFTER 12 WEEKS, TWICE-DAILY USE* Average Result**

*Unretouched clinical photography on clean, product-free skin. **In all study patients, mean improvements in the appearance of Global Skin Quality from baseline were 13% after 2 weeks, 22% after 4 weeks, 30% after 8 weeks and 39% after 12 weeks (N=53).

Mystro Active Balance Serum

5X AWARD WINNER

ADAPT + BALANCE

After 12 weeks of twice-daily use, patients agree † :

+ 100% Reported an improvement in the overall quality of their facial skin + 98% Felt more confident in the appearance of their skin + 87% Said family and friends noticed or commented on their skin’s improved appearance + 82% Wore less makeup after using Mystro Active Balance Serum

BEFORE

AFTER 2 WEEKS, TWICE-DAILY USE* Above Average Result**

BEFORE

AFTER 8 WEEKS, TWICE-DAILY USE* Above Average Result**

† A 12-week, dermatologist-led clinical trial evaluated improvements in appearance and patient satisfaction from baseline in 53 patients with mild-to-severe photo-damaged skin. Mystro Active Balance Serum was used twice daily in conjunction with a gentle cleanser (AM/PM), Hydration Boosting Cream (AM/PM) and sun better SHEER SPF 56 Sunscreen Stick (AM).

BioRewind Skin Health Dietary Supplement

NEW!

DIETARY SUPPLEMENT - SKIN HEALTH

A clinically tested skin health dietary supplement that reverses glycation by reducing the formation of Advanced Glycation End products (AGEs), harmful byproducts of glycation that stiffen collagen and elastin resulting in visible signs of skin aging.

MEAN IMPROVEMENT in the appearance of Global Skin Quality * after 12 weeks

17%

BASELINE

AFTER 12 WEEKS USE** Above Average Result***

BASELINE

AFTER 12 WEEKS USE** Average Result***

*Results based on a 12-week double-blinded, randomized trial conducted on 52 subjects. **Unretouched clinical photography on clean, product-free skin. ***Image description averages were quantified based on average improvements of Global Skin Quality assessed by the investigator from Baseline over 12 weeks based on the clinically tested regimen (n=52).

Trio Rebalancing Moisture Treatment Trio Rebalancing Moisture Treatment

4X AWARD WINNER 4X AWARD WINNER

MOISTURIZER

This high-performance, triple-action formula delivers heavy hydration, without the weight, to help rebalance a compromised barrier and bring moisture back to the skin.

MEAN IMPROVEMENT in the appearance of Skin Brightness † after 8 weeks

144%

AFTER 4 WEEKS, TWICE-DAILY USE* Average Result, Global Improvement Score**

BASELINE

AFTER 4 WEEKS, TWICE-DAILY USE* Above Average Result, Global Improvement Score**

BASELINE

† Average improvement evaluated in a board-certified dermatologist-led clinical trial in 40 patients with twice-daily use over 8 weeks from baseline. *Unretouched clinical photography on clean, product-free skin. **Image descriptions were based on average measurements of global improvement assessed by investigators.

Trio Rebalancing Moisture Treatment Trio Luxe Moisture Treatment

4X AWARD WINNER 2X AWARD WINNER

MOISTURIZER

Rich hydration that's worth its weight. Works to replenish dull, dehydrated skin and for a healthier-looking appearance and improved skin texture.

MEAN INCREASE IN Hydration † after 8 weeks

116%

AFTER 4 WEEKS, TWICE-DAILY USE* Average Result, Measured by Corneometer**

BASELINE

AFTER 8 WEEKS, TWICE-DAILY USE* Above Average Result, Measured by Corneometer**

BASELINE

† Corneometer Mean Percent Improvement. An 8-week, dermatologist-led clinical trial evaluated improvements in skin hydration (Corneometer) from baseline in 27 subjects with moderate-to-severe dry, dehydrated skin following twice-daily use of Trio Luxe Moisture Treatment. *Unretouched clinical photography on clean, product-free skin. **Typicality grading is based on average measurement of skin hydration measured by corneometer. Images depict overall benefits of hydration.

Hydration Boosting Cream

AWARD WINNER

M MO IOSITSUTRUIRZIEZRE R

A dual-action moisturizer that uses a unique combination of ceramides and botanical lipids to deliver immediate and long-lasting hydration. • Excellent in combination with treatment products, retinoids and exfoliators • Enhances skin’s natural moisture retention • Improves and maintains long-term skin hydration • Helps improve the look of elasticity and feel of firmness • Excellent add-on to any skincare regimen for additional moisturization

*Results based on a 12-week study conducted on 49 subjects with mild-to-moderate dry, flaky, crepey skin on the arms with nightly application of AlphaRet Body Overnight Cream. **Unretouched clinical photography on clean, product-free skin. Images represent an average / above average result based on expert assessment from baseline at 12 weeks following nightly use (N=49).

InterFuse Treatment Cream FACE & NECK

TARGETED TREATMENT - FACE & NECK

A cutting-edge approach to supporting signs of collagen and elastin loss for visibly firmer, younger-looking skin.

After 12 weeks of twice-daily use,

92% of patients reported skin on the face : + Looks and feels firmer + Looks plumper and less crepey or wrinkled 86% of patients reported skin on the neck : + Feels firmer + Feels smoother and more supple + Looks less crepey or wrinkled

FITZPATRICK SKIN TYPE IV

BASELINE

AFTER 12 WEEKS, TWICE-DAILY USE* Average Result**

FITZPATRICK SKIN TYPE II

BASELINE

AFTER 12 WEEKS, TWICE-DAILY USE* Average Result***

*Unretouched clinical photography on clean, product-free skin using standardized digital imaging. **Image descriptions are based on average measurements of tactile firmness improvement assessed by the investigator from baseline after 12 weeks of use. (N=52) ***Image descriptions are based on average measurements of improvement in lines (fine lines/ wrinkles) assessed by the investigator from baseline after 12 weeks of use. (N=52)

InterFuse Intensive Treatment LINES

TARGETED TREATMENT - FACE

A no-needle, hyaluronic acid solution that improves the appearance of deep expression lines and wrinkles and can be complementary to in-office treatments.

IMPROVEMENT in the targeted area of

31%

Crow's Feet * after 8 weeks

IMPROVEMENT in the targeted area of Forehead Lines * after 8 weeks of patients demonstrated IMPROVEMENT in Nasolabial Folds * after 8 weeks

23%

68%

BASELINE

AFTER 4 WEEKS, TWICE-DAILY USE**

*Average improvement evaluated in a board-certified dermatologist-led clinical trial in 25 patients with twice-daily use over 8 weeks from baseline. **Unretouched clinical photography on clean, product-free skin. BASELINE AFTER 8 WEEKS, TWICE-DAILY USE**

231

Even Tone Correcting Serum

3X AWARD WINNER

TARGETED TREATMENT - FACE

Features b.r.y.t. Technology, a ground- breaking, non-retinol, non-hydroquinone formula that delivers a visibly dramatic reduction in the appearance of hyper- pigmentation, improves overall tone and evenness of the skin's appearance.

IMPROVEMENT in the appearance of Hyperpigmentation * after 12 weeks

31%

After 12 weeks of twice-daily use, 96% of patients agreed: + The appearance of uneven skin tone or discoloration was reduced + The look of darker patches was lightened + The evenness of skin was improved

BASELINE

AFTER 12 WEEKS, TWICE-DAILY USE**

*Average improvement evaluated in a board-certified dermatologist-led clinical trial in 52 patients with twice-daily use over 12 weeks from baseline. **Unretouched clinical photography on clean, product-free skin. BASELINE AFTER 12 WEEKS, TWICE-DAILY USE**

AlphaRet Exfoliating Peel Pads

3X AWARD WINNER

TARGETED TREATMENT - FACE

Boost your skin bette r glow with these exfoliating pads featuring our award-winning retinoid, AlphaRet, along with a triple-acid blend of glycolic, lactic and salicylic acid, in individually packaged pads. †

With only 3 weeks of use in the evening (3 uses per week), 80% of patients reported: + Skin was healthier looking + Overall appearance of their skin was improved + Skin was smoother looking + They would continue to use the product at the conclusion of the study

BASELINE

AFTER 3 WEEKS*

BASELINE

AFTER 3 WEEKS*

*Average improvement evaluated in a board-certified dermatologist-led clinical trial in 22 patients with 3x per week use in the evening over 3 weeks in combination with twice-daily use of Trio Rebalancing Moisture Treatment from baseline. Unretouched clinical photography on clean, product-free skin. † See sunburn alert and caution statements.

EyeMax AlphaRet Overnight Cream

3X AWARD WINNER

TARGETED TREATMENT - EYE

A rich, silky overnight eye cream, featuring the power of the award-winning AlphaRet Technology, designed to deeply hydrate, revitalize and smooth the appearance of the skin around the eye area. †

IMPROVEMENT in the appearance of Under-eye Dryness * after 12 weeks IMPROVEMENT in the appearance of Under-eye Puffiness * after 12 weeks

94%

55%

BASELINE

AFTER 8 WEEKS, NIGHTLY USE**

After 8 weeks of combination use with InterFuse Treatment Cream EYE, 100% of patients: + Experienced an improvement in the appearance of skin under their eyes

BASELINE

AFTER 12 WEEKS USE***

*Average improvement evaluated in a board-certified dermatologist-led clinical trial in 29 patients with nightly use over 12 weeks from baseline. **Unretouched clinical photography on clean, product-free skin. ***Combination use of InterFuse Treatment Cream EYE (AM) and EyeMax AlphaRet Overnight Cream (PM). Not clinically tested for use on the eyelids. † See caution statement.

InterFuse Treatment Cream EYE

2X AWARD WINNER

TARGETED TREATMENT - EYE

A powerful, award-winning eye recharger that provides multiple benefits and reveals a more youthful-looking, rested eye area.

≥ 1-GRADE IMPROVEMENT in the appearance of Under-eye Bags * after 8 weeks ≥ 1-GRADE IMPROVEMENT in the appearance of Fine Lines & Wrinkles * after 8 weeks

54%

58%

BASELINE

AFTER 4 WEEKS, TWICE-DAILY USE**

Instant Effect Gel EYE

TARGETED TREATMENT - EYE

A refreshing daily eye gel for more resilient- looking skin. Improves the look of firmness and tightness of the skin around the eyes, while the cooling gel and stainless-steel rollerball applicator provide hydration to the skin.

IMPROVEMENT in the appearance of Fine Lines & Wrinkles * after 28 days IMPROVEMENT in the appearance of Skin Texture * after 28 days IMPROVEMENT in the appearance of Under-eye Bags * after 28 days

32%

30%

16%

BASELINE

AFTER 28 DAYS, TWICE-DAILY USE**

*Average improvement evaluated in a board-certified dermatologist-led clinical trial in 15 patients with twice-daily use over 28 days from baseline. **Unretouched clinical photography on clean, product-free skin. BASELINE AFTER 28 DAYS, TWICE-DAILY USE**

Techno Neck Perfecting Cream

4X AWARD WINNER

TARGETED TREATMENT - NECK

NOw Complex harnesses the power of the body's natural processes to visibly improve aging skin of the neck and décolleté. Skin can look firmer and more resilient, while the appearance of crepiness, laxity and texture improves. This formulation intensely hydrates to improve the suppleness of the skin.

After 8 weeks of twice-daily use, 96% of patients agreed the skin on their neck: + Was less crepey and saggy looking + Looked firmer and tighter + Felt more hydrated

BASELINE

AFTER 12 WEEKS, TWICE-DAILY USE*

BASELINE

AFTER 12 WEEKS USE** †

*Unretouched clinical photography on clean, product-free skin. **Average improvement evaluated in a board certified dermatologist-led clinical trial in 36 patients with twice-daily use over 12 weeks from baseline. Ten patients applied Techno Neck Perfecting Cream twice daily and AlphaRet Overnight Cream nightly to the neck and décolleté. † See sunburn alert and caution statements.

AlphaRet Body Overnight Cream

AWARD WINNER

TARGETED TREATMENT - BODY

AlphaRet Body Overnight Cream harnesses the power of AlphaRet, a unique combination of an AHA and a retinoid. Formulated to help resurface and improve the appearance of skin texture, this nightly body cream helps hydrate and smooth rough, dry, flaky skin

IMPROVEMENT in the appearance of Dryness * after 12 weeks IMPROVEMENT in the appearance of

43%

52%

Skin Texture * after 12 weeks

DRYNESS

BASELINE

AFTER 12 WEEKS NIGHTLY USE Average Result**

DRYNESS, FLAKING & SKIN TEXTURE

BASELINE

AFTER 12 WEEKS NIGHTLY USE Above Average Result**

Cleanse + Prep

CLEANSERS

Refining Foam Cleanser Normal to Oily Skin A multi-tasking, velvety-soft cleansing foam that exfoliates and renews skin. Leaves skin feeling soft and smooth with a brighter, more refined look. • Alpha hydroxy acids and salicylic acid exfoliate and purify skin • Decongests pores and removes excess surface oil • Gently cleanses and helps remove make-up • Hydrates and conditions for softer, smoother-feeling skin Cleansing Gel All Skin Types A mild, foaming gel cleanser that gently and thoroughly cleanses the skin and removes makeup. • Contains mild, sulfate-free surfactants • Features a skin-soothing blend • Ideal for daily use • Clinically tested for use on compromised or sensitive skin*

EXFOLIATING MASK

Detoxifying Scrub Mask A dual-functioning clay-based scrub mask that resets skin to deliver more clarity and glow. † • Uses gentle, biodegradable spherical beads to lightly resurface the skin • Clay minerals absorb excess oil and remove toxins and other impurities

† See sunburn alert and caution statements. *Clinical testing included evaluation of tolerability of Cleansing Gel following application of the AlphaRet Professional Peel 30 (N=15).

Skincare is Personal

Introducing curated and clinically proven product combinations designed to address the skin concerns most important to you. You can trust that these products have been clinically tested - individually and in combination - in individuals with a range of skin types and conditions.

FOUNDATIONAL FAVORITES †

New to professional skincare? These award-winning, clinically tested power players are anything but basic. Take the first step in a journey to your best skin. AGING + OILINESS + BLEMISHES † Struggling with the signs of aging AND blemish-prone skin? This regimen improves the appearance of blemish- prone skin while hydrating, soothing and rejuvenating. SKIN DISCOLORATION + UNEVEN TONE † Noticing the visible effects of aging and sun damage in the form of dullness, uneven color, brown spots, redness or even a yellow undertone in the skin? Even the look

and amp up the glow of your skin with this proven regimen.

† See sunburn alert and caution statements.

Where to Start

Regimen

FOUNDATIONAL FAVORITES 1†

REGIMEN INCLUDES: AlphaRet Overnight Cream + Alto Advanced Defense and Repair Serum With the Where to Start Regimen, aged-looking skin across a spectrum of skin tones can experience visible improvement in the overall appearance of the skin, including an improved glow and texture. After 12 weeks of regimen use 1 , physician assessment indicated that patients on average from baseline experienced:

IMPROVEMENT in the appearance of Skin Dullness IMPROVEMENT in the appearance of Skin Texture

64%

54%

After 8 weeks of regimen use, 100% of patients reported : + Skin appeared brighter , more radiant and even looking + Skin appeared healthier and more youthful looking

BASELINE

AFTER 4 WEEKS*

BASELINE

AFTER 12 WEEKS*

*Unretouched clinical photography on clean, product-free skin. † See sunburn alert and caution statements.

Clarity

Regimen

AGING + OILINESS + BLEMISHES 2†

REGIMEN INCLUDES: AlphaRet Exfoliating Peel Pads + AlphaRet Clearing Serum + Hydration Boosting Cream A tolerable, and easy-to-use regimen can help simplify the management of multiple skin concerns and deliver remarkable results. The Clarity Regimen is designed for patients dealing with both the signs of aging AND blemish-prone skin. After 12 weeks of regimen use 2 , physician assessment indicated that patients on average from baseline experienced:

IMPROVEMENT in the appearance of

Skin Clarity 52%

After 4 weeks of regimen use, 80% of patients agreed : + They felt better about themselves + Pores were less visible + Skin felt less greasy

BASELINE

AFTER 4 WEEKS*

BASELINE

AFTER 12 WEEKS*

*Unretouched clinical photography on clean, product-free skin. † See sunburn alert and caution statements.

Even Glow

Regimen

SKIN DISCOLORATION + UNEVEN TONE 3†

REGIMEN INCLUDES: Even Tone Correcting Serum + AlphaRet Overnight Cream + AlphaRet Exfoliating Peel Pads The Even Glow Regimen is designed for those specifically looking to address the appearance of brown, red and yellow discoloration that can occur from sun damage. After 12 weeks of regimen use 3 , physician assessment indicated that patients on average from baseline experienced:

IMPROVEMENT in the appearance of Hyperpigmentation 44%

After 12 weeks of regimen use, 96% of patients agreed the following improved: + The appearance of discoloration + Evenness in the skin + Overall skin tone

BASELINE

AFTER 4 WEEKS*

BASELINE

AFTER 12 WEEKS*

*Unretouched clinical photography on clean, product-free skin. † See sunburn alert and caution statements.

See more results and before and after photos:

1 Results from a 12-week study evaluating the efficacy and tolerability of Alto Advanced Defense and Repair Serum (AM/PM), in combination with AlphaRet Over - night Cream (PM) in patients with Fitzpatrick Skin Types (FST) IV-V and mild-to-mod - erate facial photodamage (N=22). 2 Results from a 12-week study evaluating the efficacy and tolerability of AlphaRet Clearing Serum, AlphaRet Exfoliating Peel Pads and Hydration Boosting Cream in patients with mild-to-moderate blemish-prone skin (N=11). 3 Even Tone Correcting Serum was clinically evaluated in a 12-week study conducted in 52 patients with mild-to-moderate photodamage. A subset of patients (N=10) in this study applied Even Tone Correcting Serum twice-daily and AlphaRet Overnight Cream nightly. *AlphaRet Exfoliating Peel Pads were not used in the study featured in this piece. Grimes PE, et al. J Drugs Dermatol . 2019;18(7): 642-648.

Notes

skin better science products are easily incorporated into your current routine, even when using other skincare products. A good rule of thumb when applying products is to apply from the lightest to heaviest con - sistency: serums and gels first, followed by lotions, and then creams. An exception to this rule is that InterFuse Intensive Treatment LINES should always be applied in the order listed below to allow for optimal delivery of this product to the skin. Skincare Regimen

AM Refining Foam Cleanser (Normal to Oily) OR Cleansing Gel (All Skin Types) InterFuse Intensive Treatment LINES Instant Effect Gel EYE OR InterFuse Treatment Cream EYE Alto Advanced Defense and Repair Serum OR Alto Defense Serum OR Solo Hydrating Defense MEN Even Tone Correcting Serum Mystro Active Balance Serum Techno Neck Perfecting Cream OR InterFuse Treatment Cream FACE & NECK Hydration Boosting Cream OR Trio Rebalancing Moisture Treatment OR Trio Luxe Moisture Treatment sun better TONE SMART SPF 75 Lotion OR sun better SHEER SPF 70 Lotion OR sun better TONE SMART SPF 68 Compact OR sun better SHEER SPF 56 Compact OR sun better SHEER SPF 56 Stick BioRewind Skin Health Dietary Supplement

38 † Sunburn Alert: These products contain alpha hydroxy acids (AHAs) that may increase your skin’s sensitivity to the sun and particularly the possibility of sunburn. Use a sun- screen, wear protective clothing and limit sun exposure while using this product and for a week afterwards.

Please check with your healthcare professional to ensure your skincare regimen is right for your skin. As you would with any changes to your skincare regimen, we recommend adding one new product at a time and slowly incorporating any additional products. PM Refining Foam Cleanser (Normal to Oily) OR Cleansing Gel (All Skin Types) Detoxifying Scrub Mask (up to 3x per week) AlphaRet Exfoliating Peel Pads (up to 3x per week) Both of these products include exfoliating ingredients. InterFuse Intensive Treatment LINES Instant Effect Gel EYE OR InterFuse Treatment Cream EYE OR EyeMax AlphaRet Overnight Cream Alto Advanced Defense and Repair Serum OR Alto Defense Serum Recommended Order of Application

Even Tone Correcting Serum Mystro Active Balance Serum AlphaRet Overnight Cream OR Intensive AlphaRet Overnight Cream OR AlphaRet Clearing Serum Techno Neck Perfecting Cream OR InterFuse Treatment Cream FACE & NECK Hydration Boosting Cream OR Trio Rebalancing Moisture Treatment OR Trio Luxe Moisture Treatment AlphaRet Body Overnight Cream BioRewind Skin Health Dietary Supplement

Caution: These products contain retinoid in a topical form. If you are pregnant, lactating or planning to become pregnant, consult a physician before use. If using more than one exfoliating product, irritation may occur. For complete Usage Instructions, Sunburn Alert and Caution Statements, see product packaging.

Product Descriptions

CLEANSE + PREP Refining Foam Cleanser: A multi-tasking, velvety-soft cleansing foam that exfoliates and renews skin. Leaves skin feeling soft and smooth with a brighter, more refined look.* 2 Cleansing Gel: A mild, foaming gel cleanser that gently and thoroughly cleanses ENHANCED EXFOLIATION (for use up to 3x per week) Detoxifying Scrub Mask: Clay-based scrub mask that uses biodegradable spherical beads and a botanical extract to exfoliate skin* 2 AlphaRet Exfoliating Peel Pads: A retinoid and an AHA, along with a triple-acid blend of glycolic, lactic and salicylic acid* 1,2 TARGETED EYE TREATMENTS Instant Effect Gel EYE: Refreshing daily eye gel InterFuse Treatment Cream EYE: Award-winning eye cream to recharge the eye area EyeMax AlphaRet Overnight Cream: A proprietary combination of a retinoid and an AHA, in an optimized formulation for the delicate eye area 1 ANTIOXIDANTS Alto Advanced Defense and Repair Serum: The new gold standard in comprehensive (environmental AND intrinsic) antioxidant defense Alto Defense Serum: Vitamins C and E, plus 17 additional environmental free-radical fighters Solo Hydrating Defense MEN: Once-daily skincare, engineered for men TARGETED FACE & NECK TREATMENTS InterFuse Intensive Treatment LINES: No-needle, hyaluronic acid solution for deep expression lines Even Tone Correcting Serum: A lightweight, multi-action skin tone serum InterFuse Treatment Cream FACE & NECK: A cutting-edge approach to supporting signs of collagen and elastin loss for visibly firmer, younger-looking skin Techno Neck Perfecting Cream: Harnesses the power of the body’s natural processes to improve the visible effects of aging neck and décolleté skin TARGETED BODY TREATMENT AlphaRet Body Overnight Cream: A retinoid combined with an AHA, optimized to resurface rough, dry and crepey skin on the body* 1,2

ADAPT + BALANCE Mystro Active Balance Serum: A new way to achieve visible improvement in skin quality and glowing skin by uniquely supporting skin’s natural ability to adapt to stress and maintain balance SKIN HEALTH DIETARY SUPPLEMENT BioRewind Skin Health Dietary Supplement: A clinically tested, breakthrough skin health dietary supplement that helps reverse glycation and reduce skin redness, dullness, and rough texture. RETINOIDS AlphaRet Overnight Cream: A retinoid combined with an AHA* 1,2 Intensive AlphaRet Overnight Cream: A retinoid combined with an AHA and a higher concentration of glycolic acid for enhanced rejuvenation* 1,2 AlphaRet Clearing Serum: A retinoid combined with an AHA and formulated with salicylic acid, a beta hydroxy acid, for oilier, blemish-prone skin* 1,2 MOISTURIZERS Hydration Boosting Cream: Dual-action moisturizer that delivers immediate and long-lasting hydration Trio Rebalancing Moisture Treatment: Light-weight moisturizer with a silky feel that provides a triple action approach to improve skin hydration Trio Luxe Moisture Treatment: Rich moisturizer with a velvety feel that provides a triple action approach to improve skin hydration SUNSCREENS sunbetter TONE SMART SPF 75 Lotion: Our highest level of sun protection in a tone-adapting, creamy lotion that provides a hint of color sunbetter SHEER SPF 70 Lotion: Our highest level of sheer sun protection in a resilient, creamy lotion sunbetter TONE SMART SPF 68 Compact: High level of sun protection in a tone-adapting, silky smooth compact that provides a hint of blendable color sunbetter SHEER SPF 56 Compact: High level of sun protection in a weightless, transparent, silky smooth formula and elegant compact sunbetter SHEER SPF 56 Stick: High level of sun protection in a weightless, transparent, and easy-to-apply stick *Sun Sensitivity Statement: These products contain alpha hydroxy acids (AHAs) that may increase your skin’s sensitivity to the sun and particularly the possibility of sunburn. Use a sunscreen, wear protective clothing, and limit sun exposure while using this product and for a week afterwards. Caution: 1 AlphaRet products contain retinoid in a topical form. If you are pregnant, lactating or planning to become pregnant, consult a physician before use. 2 If using more than one exfoliating product, irritation may occur. For complete Usage Instructions, Sunburn Alert and Caution Statements, see product packaging. 41

Notes

Connect. For skincare news, tips and tricks, visit us online at skin better .com/blog.

Purchase. skin better science products are available only through authorized physicians. To purchase, contact your skincare professional or visit our website to find an authorized provider, skinbetter.com/how-to-buy.

skin better science Phoenix, AZ 85018 800.538.5600 support@skinbetter.com

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